BY Leslie Wolfe, Ph.D., Senior Vice President, Head of Chemistry, Manufacturing & Controls

Science is all about change – making new discoveries that propel us forward. In my career, this change has been reflected in how we’re able to manufacture and deliver the medicines that people need.

Sometimes change is incremental. Other times, it launches us into a new era.

BY PHILLIP SAMAYOA, PH.D., SENIOR VICE PRESIDENT, HEAD OF CORPORATE DEVELOPMENT

This article was originally published as a guest column on Cell & Gene.

We’re finally turning a corner on the COVID-19 pandemic, thanks in large part to the biopharma industry’s tremendous work over the past year to bring forward multiple highly effective vaccines.

Yet it is equally important to

A CONVERSATION WITH OUR CHIEF MEDICAL OFFICER DOUG KERR, MD, PHD, MBA

In March we recognize Bleeding Disorders Awareness Month and the communities affected by these conditions, including hemophilia. As we continue to advance our efforts toward a durable, redosable gene therapy for hemophilia A, we reflect on how we hope to serve these communities.

by SONIA RAZZETTI, PhD, VICE PRESIDENT OF QUALITY

Quality is a mindset that enables our science at Generation Bio.

It’s all about rigor. Responsibility. Integrity. And a commitment not just to do great work but to document that science so it can be understood, replicated, and built upon for years to come.

by MATTHEW STANTON, PhD, CHIEF SCIENTIFIC OFFICER

I stared at the display of cell culture images on the monitor. Every one of them was dark.

Sometimes a breakthrough comes from what is not there.

by MARK ANGELINO, PhD, FOUNDER & CHIEF OPERATING OFFICER and GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER

In the early 1940s, Pfizer executive John Smith wrote of the revolutionary drug penicillin: “[T]he yields are low, the isolation is difficult, the extraction is murder, the purification invites disaster, and the assay is unsatisfactory.”1

by GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER and DOUG KERR, MD, PhD, MBA, CHIEF DEVELOPMENT OFFICER

Thomas Edison’s first lightbulb in 1879 sparked a revolution. Using electricity that was passed through a platinum filament, his glass bulb required less power than the existing lamps of the day.

But it also lasted only a few hours before burning out.

by GEOFF MCDONOUGH, MD, President & Chief Executive Officer and DOUG KERR, MD, PhD, MBA, Chief Development Officer

This piece was originally published on WBUR’s Cognoscenti.

I want to live in a world where children have never heard of hemophilia or cystic fibrosis, because we have all but eradicated those diseases.

by GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER

This article was originally published as part of the From The Trenches feature of LifeSciVC.

Our industry stands at the beginning of the most significant opportunity to impact genetic and metabolic disease we have ever encountered –