re: Generation

October 5, 2020

Special Delivery: Engineering a non-viral delivery platform for a new class of gene therapy

by MATTHEW STANTON, PhD, CHIEF SCIENTIFIC OFFICER
I stared at the display of cell culture images on the monitor. Every one of them was dark. Sometimes a breakthrough comes from what is not there.
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AllSCIENCECULTURESTORIES
Zac and Jonathan: A brothers’ journey
"What motivated us to adopt was recognizing the need. There were kids everywhere who needed a mommy and daddy and we could do that.” — Paul
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Penny and Simon take on the world
"There is no normal. There is only life." — Danny Penny and Simon aren’t your typical brother and sister. Born from parents Danny and Jaime, who share a profound sense of wanderlust, they are already globe-hopping travelers, who have explored 12th century churches and uncovered
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What makes Generation Bio unique? Hear from our team.
by GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER
At Generation Bio, we believe that culture is shaped by everyone in our community — each employee using their unique skills, experiences and personality to help us achieve our collective mission.
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Manufacturing a global revolution in gene therapy
by MARK ANGELINO, PhD, FOUNDER & CHIEF OPERATING OFFICER and GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER
In the early 1940s, Pfizer executive John Smith wrote of the revolutionary drug penicillin: “[T]he yields are low, the isolation is difficult, the extraction is murder, the purification invites disaster, and the assay is unsatisfactory.”1
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Moving forward: How our new space powers our mission to bring next generation gene therapies to patients
Although we do affectionately refer to it as “301,” our new headquarters is more than an address. It’s an integral part of who we are, what we value, and what we aim to achieve. We are dedicated to fostering a culture where everyone
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Bringing the light of gene therapy to more patients
Thomas Edison’s first lightbulb in 1879 sparked a revolution. Using electricity that was passed through a platinum filament, his glass bulb required less power than the existing lamps of the day. But it also lasted only a few hours before burning out.
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Genetic diseases steal too many kids' futures. It doesn’t have to be this way.
by GEOFF MCDONOUGH, MD, President & Chief Executive Officer and DOUG KERR, MD, PhD, MBA, Chief Development Officer
This piece was originally published on WBUR’s Cognoscenti. I want to live in a world where children have never heard of hemophilia or cystic fibrosis, because we have all but eradicated those diseases. This isn’t a dream. The biotech industry is beginning
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Right from the beginning: returning to the origins of the orphan drug movement
by GEOFF MCDONOUGH, MD, PRESIDENT & CHIEF EXECUTIVE OFFICER
This article was originally published as part of the From The Trenches feature of LifeSciVC. Our industry stands at the beginning of the most significant opportunity to impact genetic and metabolic disease we have ever encountered – the ability to decisively intervene in the perinatal period with therapies capable of lifelong
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Take a seat at the table.

We are always looking for those who are ready to share their vision, talent, and tenacity—who believe in our mission and themselves.

Imagine a world without genetic disease.

What do you see? More health? Fewer doctor appointments? More bike riding? More peanut butter and jelly sandwiches? More life?
See our shared vision.
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